Genetic Factors in Mental Health: Depression, ADHD & Dementia

This week, we explore the genetic basis of mental health disorders like depression, anxiety, ADHD, and dementia.

Around 15% of the Indian population suffers from a mental health disorder, including depression, anxiety, bipolar disorder, and schizophrenia

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To manage mental health, it's crucial to understand the interplay between genetics, brain chemistry, experiences, and social contexts.

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Genetics play a role in depression risk. An average person has a 20-30% risk, while someone with a family history has 2-3 times greater risk. Specific genes are linked to depression susceptibility.

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Bipolar disorder is highly heritable. A rare genetic variation on chromosome 16 is associated with higher risk. Genetics also influence PTSD susceptibility.

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Borderline personality disorder has a 40% heritability. Genes linked to emotional control and impulsivity may be involved.

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ADHD can be caused by gene variations. Siblings or children of people with ADHD have a 9 times greater risk.

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OCD can be linked to genes affecting serotonin or brain communication.

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Dementia has various types, with Alzheimer's being the most common. The APOE gene influences Alzheimer's risk.

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Mental health is influenced by environment, personality, experiences, societal factors, and lifestyle. Equitable access to care and societal attitudes are crucial for support.

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